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splicing rbpms antibody  (Proteintech)


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    Structured Review

    Proteintech splicing rbpms antibody
    Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of <t>RBPMS</t> staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; <t>RBPMS:</t> <t>RNA</t> binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.
    Splicing Rbpms Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 80 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/splicing rbpms antibody/product/Proteintech
    Average 95 stars, based on 80 article reviews
    splicing rbpms antibody - by Bioz Stars, 2026-02
    95/100 stars

    Images

    1) Product Images from "Synapses and dendritic spines are eliminated in the primary visual cortex of mice subjected to chronic intraocular pressure elevation"

    Article Title: Synapses and dendritic spines are eliminated in the primary visual cortex of mice subjected to chronic intraocular pressure elevation

    Journal: Neural Regeneration Research

    doi: 10.4103/NRR.NRR-D-24-00394

    Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of RBPMS staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; RBPMS: RNA binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.
    Figure Legend Snippet: Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of RBPMS staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; RBPMS: RNA binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.

    Techniques Used: Injection, Control, Staining, RNA Binding Assay



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    Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of <t>RBPMS</t> staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; <t>RBPMS:</t> <t>RNA</t> binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.
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    Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of <t>RBPMS</t> staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; <t>RBPMS:</t> <t>RNA</t> binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.
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    Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of <t>RBPMS</t> staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; <t>RBPMS:</t> <t>RNA</t> binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.
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    Image Search Results


    Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of RBPMS staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; RBPMS: RNA binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.

    Journal: Neural Regeneration Research

    Article Title: Synapses and dendritic spines are eliminated in the primary visual cortex of mice subjected to chronic intraocular pressure elevation

    doi: 10.4103/NRR.NRR-D-24-00394

    Figure Lengend Snippet: Induction of OHT via magnetic microbead injection, and RGC loss. (A) Defined regions (450 µm × 320 µm) in the central, middle, and peripheral regions of the retina are indicated by boxes. Scale bar: 500 µm. (B) The IOP curve following anterior chamber injection of magnetic microbeads ( n = 10/group, mean ± SD, *** P < 0.001, vs . control; two-way analysis of variance followed by Sidak’s multiple comparisons test). (C) Representative images of RBPMS staining (Alexa Flour 488, green) in the central, middle, and peripheral regions of the retina in the NC group and on the OHT side at 4, 6, and 8 weeks. After 4, 6, and 8 weeks of OHT, the RGCs in the central, middle, and peripheral regions of the retina on the OHT side were significantly reduced compared with the NC group. Scale bars: 50 µm. (D–F) Quantification of RBPMS-positive RGCs at 4, 6, and 8 weeks post‐OHT in the central (D), middle (E), and peripheral (F) regions of the retina in the NC group and on the OHT side ( n = 6/group, mean ± SD, *** P < 0.001, two-way analysis of variance followed by Sidak’s multiple comparisons test). IOP: Intraocular pressure; NC: no-treatment control; ns: not significant; OHT: ocular hypertension; RBPMS: RNA binding protein with multiple splicing; RGC: retinal ganglion cell; w: week.

    Article Snippet: The retinas were permeabilized using 2% Triton X-100, followed by a 2-hour blocking step with 5% goat serum (Boster, Wuhan, China), and subsequently incubated overnight at 4°C with an anti-RNA binding protein with multiple splicing (RBPMS) antibody (rabbit, 1:100, ProteinTech, Rosemont, IL, USA, Cat# 15187-1-AP, RRID: AB_2238431).

    Techniques: Injection, Control, Staining, RNA Binding Assay

    Immunostaining of RNA-binding protein and mRNA Processing Factor-positive (RBPMS+) cells for the analysis of retinal ganglion cell (RGC) density in flat-mount retinas. ( a ) RBPMS+ RGCs in central ( A , B ) and peripheral areas ( C , D ) of control (CTRL) and Epicolin formulation-treated mice. Quantification was carried out on the whole retina ( b ) and on both central and peripheral areas of the retina ( c ). Scale bar corresponds to 50 μm. The data were plotted as means ± SEMs (n = 12 retinas per group). * p ≤ 0.05 vs. CTRL; ° p ≤ 0.05 vs. CTRL c; † p ≤ 0.05 vs. CTRL p. Unpaired t -test. CTRL central (CTRL c), CTRL periphery (CTRL p), Epicolin central (Epicolin c), and Epicolin periphery (Epicolin p).

    Journal: Pharmaceutics

    Article Title: Retinal Protection of New Nutraceutical Formulation

    doi: 10.3390/pharmaceutics17010073

    Figure Lengend Snippet: Immunostaining of RNA-binding protein and mRNA Processing Factor-positive (RBPMS+) cells for the analysis of retinal ganglion cell (RGC) density in flat-mount retinas. ( a ) RBPMS+ RGCs in central ( A , B ) and peripheral areas ( C , D ) of control (CTRL) and Epicolin formulation-treated mice. Quantification was carried out on the whole retina ( b ) and on both central and peripheral areas of the retina ( c ). Scale bar corresponds to 50 μm. The data were plotted as means ± SEMs (n = 12 retinas per group). * p ≤ 0.05 vs. CTRL; ° p ≤ 0.05 vs. CTRL c; † p ≤ 0.05 vs. CTRL p. Unpaired t -test. CTRL central (CTRL c), CTRL periphery (CTRL p), Epicolin central (Epicolin c), and Epicolin periphery (Epicolin p).

    Article Snippet: Primary antibody for RNA binding protein, mRNA Processing Factor (RBPMS, RNA-binding protein with multiple splicing), was purchased from Novus Biologicals, part of Bio-Techne SRL (Milan, Italy).

    Techniques: Immunostaining, RNA Binding Assay, Control, Formulation